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Hare, MD, ISCI founding director and sponsor of the study. “This is the first time these types of cells are being used in infants, so this is very exciting.” The Interdisciplinary Stem Cell Institute has grown from a local research center to a national cell manufacturing facility. ISCI provides cells for the Cardiovascular Cell Therapy Research Network, has been named a Production Assistance for Cellular Therapies Center by the National Heart, Lung and Blood Institute, and has been conducting research in stem cell use for cardiovascular repair since 2008. Study Details HLHS is one of the most challenging and complex congenital heart diseases to treat. The Centers for Disease Control and Prevention (CDC) estimates that about 960 babies in the United States are born each year with HLHS. For unknown reasons, the heart’s main pumping chamber, the left ventricle, does not develop completely during a critical growth period just prior to birth. The right ventricle normally pumps blood to the lungs at low pressure to be oxygenated, while the left ventricle pushes blood at high pressure through the aorta to the entire body. In children with HLHS, the right heart assumes the extra workload, temporarily supporting the circulation to both the lungs and body. That stress can cause the right heart to fail and the baby to die. Current HLHS treatment options are either a heart transplant or a series of three open-heart reconstructive surgical procedures to connect the left and right sides of the heart. However, even with a transplant or the reconstructive surgical series, children with HLHS have an average five-year survival of only 50-60 percent.http://iansanchezbest.haralsoncounty.org/2016/10/04/the-fundamentals-of-deciding-on-details-in-application-form-for-doctor
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